Peptide Database

Peptide NameOrinthodoros defensin A

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC158H250N54O45S7

DescriptionStandard

        GCGCPLNQGACHRHCKSIGRRGGYCAGFLKQTCTCY
    

Molecular Weight3850.47 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)4.86

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.1350

GRAVY Index-0.32

Hydrophobic Moment 0.74

Boman Index-0.06

Instability Index65.12

Aliphatic Index 38.06

Aromaticity 0.0833

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1598.55

LogP -21.74

H-bond Donors 64.0

H-bond Acceptors 59.0

Rotatable Bonds 124.0

Heavy Atoms 264.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164832 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithodoros coriaceus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)