Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC460H731N127O140S7

DescriptionStandard

        MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
    

Molecular Weight10504.95 Da

Isoelectric Point (pI)5.63

Net Charge (pH 7.0)-2.36

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0254

GRAVY Index-0.13

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index41.81

Aliphatic Index 82.80

Aromaticity 0.0860

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4331.32

LogP -43.38

H-bond Donors 156.0

H-bond Acceptors 147.0

Rotatable Bonds 356.0

Heavy Atoms 734.0

Ring Count 12.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421878 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence