Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length601 amino acids

Chemical FormulaC2852H4459N803O877S21

DescriptionStandard

        MPGAARLNDIGSGHACFPATPVVEGSQDVIINGQPAARQGDAIQLHGCPCPNMPHGLHPRQIAAGSSTVIINGKQAVRIGDDINCGGNIVTGSSNVIIGDTPYQSPVAGCAQQSAQRRDPLLALSPMLTIPPVFAKSCLRGEGCNDAGTEKETVDNFGQMALFAQPVVDDCCGYHRPHVNKPVVQHAQAAKKKNPSQLTEPAAASTSVQLTGSEPWYKTLYYLMSSKEIAVTPTPLAKSAITPVAAAAVPVATMSAGNTVATRAAVTTMTQVWGQVTLTEGTLAASSTVPLLGVLFAAFYSQSVGEGSDKVPGRDEHWLEDTLRQKGWAGETATTRVRFFWRSDIHGKMQVYGVHTGEGTPYEGVRVANMVWKPEQSRYEFTPAPGVDGPKITWTPANPEGSEPISQTETPVAPIDQPTILVHPIPDSAEETTTPPFPMPDEQDFNDWILVFPADSGIKPIYVYLKSTARDEPGVVTGQGEVLTGEGKWLESASSELGAPIPAQVADKLRGRTFGSFDRFREAFWMEVANDSDLSSQFNTLNIERMKHGKAPRTIKSEHAGKRKSFELHHVEHIAKGGDTYDIDNIRVATPKRHINIHREQ
    

Molecular Weight64701.13 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-9.93

Net Charge (pH 7.4) -11.32

Charge Density (pH 7.0) -0.0165

GRAVY Index-0.35

Hydrophobic Moment 0.75

Boman Index0.03

Instability Index44.66

Aliphatic Index 72.90

Aromaticity 0.0666

Extinction Coeff. Reduced 72880.00

Extinction Coeff. Oxidized 73380.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0144772 VERIFIED: YES

Provenance & Taxonomy

OrganismLonsdalea britannica [Bacterium]

FamilyPyocin

Tax ID1082704

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)