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MYP_052797
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Basic Information
beta-defensin 7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C192H325N71O47S6
Standard
Sequence
QGVRNFVTCRINRGFCVPIRCPGHRRQIGTCLGPRIKCCR
Physicochemical Analysis
4572.47 Da
11.20
8.79
8.44
0.2197
-0.26
0.76
-0.22
30.40
70.50
0.0500
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1934.57
-22.51
76.0
63.0
149.0
316.0
6.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0175037 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0175844 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
9-31; 16-38; 21-39
Bio-Activity Profile
Antimicrobial
PMID8454635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8454635/
RECORD: Rec_0310843 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPatent US 2008/0269122 A1 Evidence URLhttps://patents.google.com/patent/US20080269122A1/en PatentUS 2008/0269122 A1
RECORD: Rec_0365922 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ML35
PaperPurification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
RECORD: Rec_0417796 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 502A
PMID8454635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8454635/
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