Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length458 amino acids

Chemical FormulaC2285H3590N624O635S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGITVLEKELAQLKLPDISGDFRLRHVVKVHYEISRLNLRSFHLPYSRISLVPNVGLQVSISNAFAEMDGNWRVKMYFIRDHGSFDLNVENIYIKINLKLGSDASGKPTIDTSDCSTRISKVRVHFSGKFGWLYNLFHSAIESRFRKILESKVCENVASSVRNELQPYVRTLPVTARIDAMVGIDYSLVAPPTATAQSLDVDLKGEFFSLAHRSAVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSTVVSPRNGGLCRCPYPLPAPLQLEKMYPDTQMKLRLSTPSAPFLNIGPGGLSLRPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVIDVKSGHIVGSLKVGRYGGGAVQGGGSGGASVRMLQSIMNIFASNILLPRLNARLDQGFPLPLPDRIQLSNILVRFHPNFLLLGADVRYQPR
    

Molecular Weight50347.53 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)11.52

Net Charge (pH 7.4) 10.53

Charge Density (pH 7.0) 0.0251

GRAVY Index0.08

Hydrophobic Moment 0.70

Boman Index0.11

Instability Index40.54

Aliphatic Index 100.46

Aromaticity 0.0939

Extinction Coeff. Reduced 34840.00

Extinction Coeff. Oxidized 35090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106868 VERIFIED: NO

Provenance & Taxonomy

OrganismOceanites oceanicus (Wilson`s storm petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria