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MYP_052739
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Basic Information
Cathelicidin AM (9-36), AM-CATH28
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C147H255N41O30
Standard
Sequence
KIKKGFKKIFKRLPPIGVGVSIPLAGKR
Physicochemical Analysis
3076.85 Da
12.00
8.75
8.54
0.3126
-0.07
0.87
-0.02
16.73
107.86
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1148.82
-5.95
40.0
39.0
107.0
218.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001705 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 22192
140 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0043121 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
42 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0043914 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC BAA-1705
28 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0045925 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae ATCC 33495
5.6 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0083956 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
S-aureus ATCC 25923 or 33592
>13 μM
MIC
PaperCathelicidin antimicrobial peptide from Alligator mississippiensis has antibacterial activity against multi-drug resistant Acinetobacter baumanii and Klebsiella pneumoniae.
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