Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC756H1214N204O234S12

DescriptionStandard

        AIGLPQVISLHTILLSLGSFEPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISYEYTRRPPFRVIHLEDITFDYSDMGSFTGSPVSKLSDLVTFDARGETMTPKTNTPETTMPPSETTTSKTTMPSSKTTTSKTTMPPPSQMALTHN
    

Molecular Weight17289.73 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)4.01

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.0260

GRAVY Index-0.35

Hydrophobic Moment 0.60

Boman Index-0.03

Instability Index67.34

Aliphatic Index 70.26

Aromaticity 0.0714

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7008.41

LogP -79.49

H-bond Donors 253.0

H-bond Acceptors 253.0

Rotatable Bonds 558.0

Heavy Atoms 1206.0

Ring Count 28.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210753 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence