Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC667H1064N186O182S4

DescriptionStandard

        EPMLLLAVTDFVVNSAAFTYFTAGALHRNISDDMLPRRFPLQLKTKSMGLFSPKLQERYPNHPMELHLSARRQPLLSFRPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPLISRNRLGGTVSLKG
    

Molecular Weight14728.98 Da

Isoelectric Point (pI)10.34

Net Charge (pH 7.0)6.19

Net Charge (pH 7.4) 5.80

Charge Density (pH 7.0) 0.0466

GRAVY Index0.01

Hydrophobic Moment 0.51

Boman Index0.07

Instability Index42.45

Aliphatic Index 96.84

Aromaticity 0.0827

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5842.85

LogP -54.07

H-bond Donors 201.0

H-bond Acceptors 196.0

Rotatable Bonds 475.0

Heavy Atoms 1039.0

Ring Count 26.0

Amide Bonds 142.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066314 VERIFIED: NO

Provenance & Taxonomy

OrganismSmutsornis africanus (Double-banded courser) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria