Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length459 amino acids

Chemical FormulaC2322H3615N579O676S14

DescriptionStandard

        MIEQMAKERNIPDLKGSESLEFLKIDYVNYNFTNIKIHALSFPNTSLAFVPGVGIKALTNHGMANISTNWEVKSPLFQDTGGADLFLSGVYFTGLLILTRNDFGHPTLQLQDCYSQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIITGEVEALNANLSMLEVLTKMDNYTLLDFSLLNAPEITENNIDLDLKGVFYPLENLADPPFPSVPFVLPERSDSMLYIGISEYFFKSASFAYFTAGAFNVTLSTKEISSHLVQNSQGVGNVLSRIAEIYILSQPFMIRIMATAPPVINLLPGNFTLDIPASIVILTQPENSTVETIVSMDFVASTSVGLVILGQRLICSLSLNRFRLTLPKSSRSNIEVLRFENILSFIIHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVLEHFLLISTDLRYETSLKQQPSFHGWEGLNLISGQWSGNSAP
    

Molecular Weight50906.92 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-15.59

Net Charge (pH 7.4) -16.46

Charge Density (pH 7.0) -0.0340

GRAVY Index0.17

Hydrophobic Moment 0.64

Boman Index0.19

Instability Index40.86

Aliphatic Index 105.56

Aromaticity 0.0980

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34505.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275121 VERIFIED: NO

Provenance & Taxonomy

OrganismRousettus aegyptiacus (Egyptian rousette) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria