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MYP_052656
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Basic Information
K11 (derivative of CP-P)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
20 amino acids
C123H197N31O24
Standard
Sequence
KWKSFIKKLTKKFLHSAKKF
Physicochemical Analysis
2494.07 Da
10.85
7.84
7.57
0.3920
-0.77
0.69
-0.22
1.01
63.50
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
929.54
-3.42
34.0
33.0
90.0
178.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0092222 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
S. paratyphi B CMCC50094
2 μg/mL
MIC
PaperThe Design and Construction of K11: A Novel alpha-Helical Antimicrobial Peptide
RECORD: Rec_0099516 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
1 μg/mL
MIC
PaperPubMed PMID: 22518150 PMID22518150 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0117175 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
500 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/22518150/ PMID22518150 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0117439 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Clinical isolates: Acinetobacter baumannii b-01
0.8 μg/mL
MIC
PaperPubMed PMID: 22518150 PMID22518150 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0119213 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
Staphylococcus aureus CMCC26003 or MRSA
0.25-4 μg/mL
MIC
PaperThe Design and Construction of K11: A Novel alpha-Helical Antimicrobial Peptide
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