Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC73H114N16O19

DescriptionStandard

        GWFDIIKKIASEL
    

Molecular Weight1519.78 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0183

GRAVY Index0.38

Hydrophobic Moment 0.66

Boman Index0.27

Instability Index29.97

Aliphatic Index 127.69

Aromaticity 0.1538

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 575.18

LogP -1.39

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 51.0

Heavy Atoms 108.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181672 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyUperin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1 IIIB:inhibition the cytopathic effects of HIV-1 infection in CEM-SS cells

Activity10.7 μM

MethodEC50

RECORD: Rec_0351241 VERIFIED: YES