Peptide Database

Peptide NameResistin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC432H697N125O134S12

DescriptionStandard

        SSMPLCPIDEAIDKKIKQDFNSLFPNAIKNIGLNCWTVSSRGKLASCPEGTAVLSCSCGSACGSWDIREEKVCHCQCARIDWTAARCCKLQVAS
    

Molecular Weight10170.69 Da

Isoelectric Point (pI)8.01

Net Charge (pH 7.0)1.45

Net Charge (pH 7.4) 1.01

Charge Density (pH 7.0) 0.0154

GRAVY Index-0.04

Hydrophobic Moment 0.61

Boman Index0.01

Instability Index50.21

Aliphatic Index 75.85

Aromaticity 0.0532

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 17125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4160.80

LogP -49.18

H-bond Donors 155.0

H-bond Acceptors 149.0

Rotatable Bonds 336.0

Heavy Atoms 703.0

Ring Count 13.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000012 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyResistin

Tax ID10090

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-6; 35-88; 47-87; 56-73; 58-75; 62-77

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Feeding regulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0302683 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyResistin

Tax ID10090

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-6; 35-88; 47-87; 56-73; 58-75; 62-77

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Feeding regulator

Targetability to stimulate glucose uptake into adipose cells

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0338815 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0341325 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyResistin/FIZZ

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone-like secreted

RECORD: Rec_0398619 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Familyresistin/FIZZ family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide35-88; 47-87; 56-73; 58-75; 62-77

Bio-Activity Profile

Function

Hormone resistin FIZZ family