Peptide Database

Peptide NameGLP-1-PEG

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC188H282N46O60S2

DescriptionStandard

        HVEGTFTSDVSSYLEEQAAKEFIAWLIKGGPSSGAPPPCC
    

Molecular Weight4210.65 Da

Isoelectric Point (pI)4.57

Net Charge (pH 7.0)-3.16

Net Charge (pH 7.4) -3.46

Charge Density (pH 7.0) -0.0791

GRAVY Index-0.12

Hydrophobic Moment 0.48

Boman Index0.17

Instability Index50.48

Aliphatic Index 63.50

Aromaticity 0.1000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1651.00

LogP -17.40

H-bond Donors 57.0

H-bond Acceptors 60.0

Rotatable Bonds 129.0

Heavy Atoms 296.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159523 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGLP-1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermPEGylation

Bio-Activity Profile

Function

Insulinotropic

Activity0.00036 μM

MethodEC50

Half-LifeRat plasma (Intravenous), in vivo; 92880 s

RECORD: Rec_0328399 VERIFIED: YES