Peptide Database

Peptide NameBeta-defensin 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC515H823N147O144S8

DescriptionStandard

        GPADLPRPTFRDDQSHVASHGQVPFCIPTGWSVLLSPSVLKSLWLQARSLKCSLSLLIGVNLLTGLGQRSDHYKCVKKGGTCNFSPCPLFNRIEGTCYSGKAKCCIR
    

Molecular Weight11634.46 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)7.94

Net Charge (pH 7.4) 7.45

Charge Density (pH 7.0) 0.0742

GRAVY Index-0.05

Hydrophobic Moment 0.55

Boman Index0.05

Instability Index48.25

Aliphatic Index 85.61

Aromaticity 0.0748

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4621.26

LogP -49.61

H-bond Donors 169.0

H-bond Acceptors 163.0

Rotatable Bonds 375.0

Heavy Atoms 814.0

Ring Count 21.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038680 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera physalus [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal