Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length155 amino acids

Chemical FormulaC790H1248N218O211S7

DescriptionStandard

        QLPRQFPLQLRTKSMEVFSPELQQRYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFMVLPNATRVPAFLLNIDANVTGNPTITRNRLGGTVRLTGLVPDPELSWTTLPALCWAQGLPLPQVKRLETLLKFGLWLFGVPRANSKCCPRPVP
    

Molecular Weight17400.15 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)5.00

Net Charge (pH 7.4) 4.57

Charge Density (pH 7.0) 0.0322

GRAVY Index-0.12

Hydrophobic Moment 0.60

Boman Index0.06

Instability Index53.12

Aliphatic Index 93.74

Aromaticity 0.0774

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6758.70

LogP -57.92

H-bond Donors 230.0

H-bond Acceptors 226.0

Rotatable Bonds 544.0

Heavy Atoms 1226.0

Ring Count 38.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318002 VERIFIED: NO

Provenance & Taxonomy

OrganismOxylabes madagascariensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria