Peptide Database

Peptide Namepeptide 6

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC66H107N19O24S

DescriptionStandard

        GQPEEGAPCQVVLQGA
    

Molecular Weight1582.73 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.46

Charge Density (pH 7.0) -0.1403

GRAVY Index-0.23

Hydrophobic Moment 0.23

Boman Index0.15

Instability Index60.31

Aliphatic Index 73.12

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 686.11

LogP -8.57

H-bond Donors 21.0

H-bond Acceptors 23.0

Rotatable Bonds 49.0

Heavy Atoms 110.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0175753 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyVirus-derived peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Replication inhibitor

TargetHerpes simplex virus 1 (Replication)

Activity3.5 μM

MethodDNA polymerase assay

PaperInhibition of herpes simplex virus type 1 DNA polymerase activity by peptides from the UL42 accessory protein is largely nonspecific. | Owsianka AM, Hart G, Murphy M, Gottlieb J, Boehme R, Challberg M, Marsden HS. | J Virol. 1993 | PMID:8380075 PMID8380075 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8380075/