Peptide Database

Peptide NamePol-RFamide 1

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC36H58N10O10

DescriptionStandard

        ELLGGRF
    

Molecular Weight790.91 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) -0.0233

GRAVY Index0.23

Hydrophobic Moment 0.30

Boman Index0.14

Instability Index26.20

Aliphatic Index 111.43

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 337.12

LogP -1.97

H-bond Donors 12.0

H-bond Acceptors 10.0

Rotatable Bonds 26.0

Heavy Atoms 56.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124587 VERIFIED: YES

Provenance & Taxonomy

OrganismPolyorchis penicillatus [Animal]

FamilyPol-RFamide

Tax ID6091

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0281032 VERIFIED: YES

Provenance & Taxonomy

OrganismPolyorchis penicillatus [Animal]

FamilyFMRFamide related peptide

Tax ID6091

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0366122 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/