Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length130 amino acids

Chemical FormulaC626H985N173O199S6

DescriptionStandard

        METQRASLALGRWPLWLLLLGLVVPSASAQALSYREAVLHAVDRLNERSSEANLYPPPGDEDPDTPKPVSFTVKETVCSRTTQQPPEQCDFKENGLVKQCVGTVTLDQSKDQFDINCNEVSGPFCASRGF
    

Molecular Weight14310.95 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-5.43

Net Charge (pH 7.4) -5.81

Charge Density (pH 7.0) -0.0418

GRAVY Index-0.38

Hydrophobic Moment 0.64

Boman Index-0.03

Instability Index37.62

Aliphatic Index 76.46

Aromaticity 0.0692

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5963.29

LogP -66.53

H-bond Donors 205.0

H-bond Acceptors 201.0

Rotatable Bonds 461.0

Heavy Atoms 1004.0

Ring Count 23.0

Amide Bonds 142.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320646 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera musculus [Animal]

FamilyCathelicidin

Tax ID9771

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal