Peptide Database

Peptide NameSLAY-screened peptide P5153

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC128H170N26O27S

DescriptionStandard

        LMSPWILLLDAHWFEHFFAY
    

Molecular Weight2536.94 Da

Isoelectric Point (pI)5.15

Net Charge (pH 7.0)-2.06

Net Charge (pH 7.4) -2.37

Charge Density (pH 7.0) -0.1031

GRAVY Index0.73

Hydrophobic Moment 0.24

Boman Index0.52

Instability Index46.99

Aliphatic Index 107.50

Aromaticity 0.3000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 811.43

LogP 2.53

H-bond Donors 28.0

H-bond Acceptors 28.0

Rotatable Bonds 73.0

Heavy Atoms 182.0

Ring Count 11.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0092030 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/