Peptide Database

Peptide NameBeta defensin 1 (Beta-defensin-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC313H504N80O79S7

DescriptionStandard

        MRILHFLLAFLIVFLLPVPGFTAGIETSFSCSQNGGFCISPKCLPGSKQIGTCILPGSKCCRKK
    

Molecular Weight6876.29 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0863

GRAVY Index0.62

Hydrophobic Moment 0.48

Boman Index0.25

Instability Index52.25

Aliphatic Index 97.50

Aromaticity 0.0938

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2483.89

LogP -20.82

H-bond Donors 91.0

H-bond Acceptors 93.0

Rotatable Bonds 223.0

Heavy Atoms 479.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216549 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0362782 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence