Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC793H1246N190O211S6

DescriptionStandard

        TFVFNPSLYFLYLSQIPKTSPFRLNTTSFGPLIPQLPKLFPNMLMELQVYARNVPIFSFQADKVTMEFPGAVKAFAIQPNASRTPLFKLNVDSIFSGMIRISEEKLKGLVELSNFTLTLASSEVGTFQTAALEKFMKLGMKISVLAKLNGKF
    

Molecular Weight17009.91 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)6.41

Net Charge (pH 7.4) 6.18

Charge Density (pH 7.0) 0.0421

GRAVY Index0.24

Hydrophobic Moment 0.68

Boman Index0.18

Instability Index23.65

Aliphatic Index 95.59

Aromaticity 0.1250

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6385.51

LogP -48.86

H-bond Donors 215.0

H-bond Acceptors 224.0

Rotatable Bonds 559.0

Heavy Atoms 1200.0

Ring Count 30.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378695 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyBPI/LBP

Tax ID8022

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria