Peptide Database

Peptide NameScorpions-Ticks Defensins Ancestor, STiDA

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC268H406N82O71S7

DescriptionStandard

        GGFGCPFNIDNQGNCHNHCQSIRGRKGGYCHGIFKQTCKCYKPMGYKTRPPFILG
    

Molecular Weight6137.05 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)6.96

Net Charge (pH 7.4) 6.50

Charge Density (pH 7.0) 0.1265

GRAVY Index-0.68

Hydrophobic Moment 0.54

Boman Index-0.06

Instability Index51.87

Aliphatic Index 35.45

Aromaticity 0.1273

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2461.71

LogP -27.85

H-bond Donors 89.0

H-bond Acceptors 88.0

Rotatable Bonds 198.0

Heavy Atoms 428.0

Ring Count 14.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254695 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetPlasmodium falciparum[40-50% Inhibition = 50 microM]

RECORD: Rec_0344946 VERIFIED: YES