Peptide Database

Peptide NameP97(derived from E2 envelope protein of GB virus C)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC86H154N34O23S2

DescriptionStandard

        LVRRRSELMGRRNPVCPG
    

Molecular Weight2096.49 Da

Isoelectric Point (pI)11.82

Net Charge (pH 7.0)3.75

Net Charge (pH 7.4) 3.53

Charge Density (pH 7.0) 0.2085

GRAVY Index-0.77

Hydrophobic Moment 0.53

Boman Index-0.44

Instability Index166.68

Aliphatic Index 75.56

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 950.56

LogP -10.95

H-bond Donors 36.0

H-bond Acceptors 29.0

Rotatable Bonds 69.0

Heavy Atoms 145.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341636 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1:inhibition of gp41-induced cell-cell fusion in CEM-174 cells

Activity537.6 μM

MethodIC50

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