Peptide Database

Peptide NameDefensin-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC458H725N129O141S9

DescriptionStandard

        MKSITVICFLALCTVAITSAYPQEPVLADEARPFANSLFDELPEETYQAAVENFRLKRATCDLLSGFGVGDSACAAHCIARGNRGGYCNSQKVCVCRN
    

Molecular Weight10583.02 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.88

Charge Density (pH 7.0) -0.0151

GRAVY Index0.11

Hydrophobic Moment 0.61

Boman Index0.07

Instability Index40.72

Aliphatic Index 81.73

Aromaticity 0.0816

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4329.94

LogP -48.06

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 343.0

Heavy Atoms 737.0

Ring Count 13.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290075 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-positive Non-hemolytic

TargetGram Positive Bacteria