Peptide Database

Peptide NameCycloviolacin H1

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC132H216N36O41S6

DescriptionStandard

        CGESCVYIPCLTSAIGCSCKSKVCYRNGIP
    

Molecular Weight3155.73 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0566

GRAVY Index0.41

Hydrophobic Moment 0.32

Boman Index0.14

Instability Index20.07

Aliphatic Index 74.67

Aromaticity 0.0667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1225.58

LogP -15.03

H-bond Donors 49.0

H-bond Acceptors 49.0

Rotatable Bonds 99.0

Heavy Atoms 215.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373392 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-HIV

TargetHuman erythrocytes

Activity20 μM

MethodHemolysis

RECORD: Rec_0413315 VERIFIED: YES