Peptide Database

Peptide NamePutative colicin activity protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length136 amino acids

Chemical FormulaC531H794N168O180S2

DescriptionStandard

        MSGGDGRGHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGHGNGGGNGNSGGGSNSSVAAVAFGFPALAAPGAGTLGIAVSGEALSAAIADIFAALKGPFKFSAWGNCALQHSAI
    

Molecular Weight12475.13 Da

Isoelectric Point (pI)6.14

Net Charge (pH 7.0)-2.07

Net Charge (pH 7.4) -2.56

Charge Density (pH 7.0) -0.0152

GRAVY Index-0.15

Hydrophobic Moment 0.45

Boman Index0.25

Instability Index23.05

Aliphatic Index 54.04

Aromaticity 0.0662

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5419.64

LogP -89.78

H-bond Donors 185.0

H-bond Acceptors 185.0

Rotatable Bonds 395.0

Heavy Atoms 881.0

Ring Count 23.0

Amide Bonds 148.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0273780 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Bacteriocin

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence