Peptide Database

Peptide NameU1-theraphotoxin-Hhn1a

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC175H247N49O52S6

DescriptionStandard

        ECKYLWGTCEKDEHCCEHLGCNKKHGWCGWDGTFG
    

Molecular Weight4061.52 Da

Isoelectric Point (pI)5.80

Net Charge (pH 7.0)-1.96

Net Charge (pH 7.4) -2.38

Charge Density (pH 7.0) -0.0559

GRAVY Index-0.92

Hydrophobic Moment 0.30

Boman Index-0.06

Instability Index31.29

Aliphatic Index 22.29

Aromaticity 0.1429

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1617.79

LogP -14.84

H-bond Donors 62.0

H-bond Acceptors 59.0

Rotatable Bonds 131.0

Heavy Atoms 282.0

Ring Count 11.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014940 VERIFIED: NO

Provenance & Taxonomy

OrganismSelenocosmia hainana [Animal]; Haplopelma hainanum [Animal]; Ornithoctonus hainana [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-16, 9-21, 15-28

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0335183 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic