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MYP_052281
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Basic Information
gH493-512(derived from HSV-1 H glycoprotein)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C98H155N25O28
Standard
Sequence
AAHLIDALYAEFLGGRVLTT
Physicochemical Analysis
2131.43 Da
5.32
-1.11
-1.36
-0.0557
0.79
0.34
0.35
23.27
132.00
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
842.09
-5.64
30.0
28.0
67.0
151.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056539 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus type 1
60 %
Inhibition
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0080898 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus type 1(HSV-1) | Vero cells
250 μM
% inhibition
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperPeptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity. | Galdiero S, Falanga A, Vitiello M, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M. | Peptides. 2008 Sep;29(9):1461-71. | DOI:10.1016/j.peptides.2008.04.022 | PMID:18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0086488 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
toxicity against Vero cells up to 500 μM
500 μM
Cytotoxicity
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0109605 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
RECORD: Rec_0116392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 18572274 PMID18572274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18572274/
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