Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC435H670N126O124S9

DescriptionStandard

        MKYFTMFAFFFVAVCYISQSSASPAPKEEANFVHGADALKQLEPELHGRYKRATCDLLSGTGVGHSACAAHCLLRGNRGGYCNGKGVCVCRN
    

Molecular Weight9937.33 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)3.78

Net Charge (pH 7.4) 3.24

Charge Density (pH 7.0) 0.0411

GRAVY Index-0.04

Hydrophobic Moment 0.54

Boman Index0.07

Instability Index36.04

Aliphatic Index 64.78

Aromaticity 0.1087

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3984.70

LogP -43.50

H-bond Donors 146.0

H-bond Acceptors 141.0

Rotatable Bonds 322.0

Heavy Atoms 694.0

Ring Count 17.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291917 VERIFIED: NO

Provenance & Taxonomy

OrganismMusca domestica [Animal]

FamilyDefensin

Tax ID7370

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal