Peptide Database

Peptide NameAntimicrobial peptide Con22

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC409H658N100O110S6

DescriptionStandard

        MNAKVMLVCLLVTMLVMEPAEAGIWSWIKKTAKKVWNSDVAKKLKGKALNVAKDFVAEKIGATPAEAGQIPFDEFMNVLYS
    

Molecular Weight8928.59 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.24

Charge Density (pH 7.0) 0.0308

GRAVY Index0.24

Hydrophobic Moment 0.67

Boman Index0.17

Instability Index12.00

Aliphatic Index 98.77

Aromaticity 0.0864

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3354.00

LogP -21.55

H-bond Donors 114.0

H-bond Acceptors 119.0

Rotatable Bonds 301.0

Heavy Atoms 625.0

Ring Count 13.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015184 VERIFIED: NO

Provenance & Taxonomy

OrganismUrodacus yaschenkoi [Animal]

FamilyNon-disulfide-bridged peptide (NDBP) superfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Antifungal Fungicide Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence