Peptide Database

Peptide NameCecropin

Function Ontology

—

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC129H220N42O34

DescriptionStandard

        GWLRKLGKKIERIGQHTRDASIQVL
    

Molecular Weight2903.39 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.1539

GRAVY Index-0.60

Hydrophobic Moment 0.98

Boman Index-0.19

Instability Index28.53

Aliphatic Index 109.20

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1271.19

LogP -11.01

H-bond Donors 46.0

H-bond Acceptors 39.0

Rotatable Bonds 103.0

Heavy Atoms 205.0

Ring Count 3.0

Amide Bonds 26.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0056044 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila sechellia [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)