Peptide Database

Peptide NameGrowth/differentiation factor 11

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC545H825N149O159S14

DescriptionStandard

        NLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
    

Molecular Weight12457.19 Da

Isoelectric Point (pI)7.67

Net Charge (pH 7.0)0.94

Net Charge (pH 7.4) 0.42

Charge Density (pH 7.0) 0.0086

GRAVY Index-0.45

Hydrophobic Moment 0.41

Boman Index-0.02

Instability Index36.58

Aliphatic Index 54.59

Aromaticity 0.1193

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4930.17

LogP -48.99

H-bond Donors 176.0

H-bond Acceptors 177.0

Rotatable Bonds 398.0

Heavy Atoms 867.0

Ring Count 26.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162930 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide15-74; 43-106; 47-108

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling