Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC449H729N123O140S8

DescriptionStandard

        MTTLTLLTAILLVLLQAQAGPLQARADEATAAQEQPGTDDQDFAISCSISPAFSVFPGSTRRLVCSCRLVFCQRTELRVGNCVIGGISFTYCCSLVD
    

Molecular Weight10346.85 Da

Isoelectric Point (pI)4.81

Net Charge (pH 7.0)-2.55

Net Charge (pH 7.4) -2.88

Charge Density (pH 7.0) -0.0263

GRAVY Index0.44

Hydrophobic Moment 0.59

Boman Index0.16

Instability Index44.07

Aliphatic Index 99.59

Aromaticity 0.0619

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4200.42

LogP -47.60

H-bond Donors 153.0

H-bond Acceptors 146.0

Rotatable Bonds 335.0

Heavy Atoms 720.0

Ring Count 10.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301377 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic