Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC888H1443N267O248S5

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLVLPSASAQALSYREAVLRAVDRINERSSEANLYRLLELDPPPKDVEDRGARKPTSFTVKETVCPRTSPQPPEQCDFKENGLVKQCVGTITLDQSDDLFDLNCNELQSVRRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPL
    

Molecular Weight19987.92 Da

Isoelectric Point (pI)10.31

Net Charge (pH 7.0)9.49

Net Charge (pH 7.4) 9.18

Charge Density (pH 7.0) 0.0539

GRAVY Index-0.65

Hydrophobic Moment 0.84

Boman Index-0.18

Instability Index53.68

Aliphatic Index 83.64

Aromaticity 0.0511

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8190.01

LogP -94.67

H-bond Donors 282.0

H-bond Acceptors 263.0

Rotatable Bonds 627.0

Heavy Atoms 1408.0

Ring Count 41.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0292749 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence