Peptide Database

Peptide NameDefensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC447H719N127O132S8

DescriptionStandard

        VYFLVALLFVAVAAIMAAPVEEEYELLEQAGIEERADRQRRVTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGVCLCRKTNFKDLWDKRFG
    

Molecular Weight10240.78 Da

Isoelectric Point (pI)5.82

Net Charge (pH 7.0)-1.22

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0131

GRAVY Index0.10

Hydrophobic Moment 0.49

Boman Index0.04

Instability Index42.81

Aliphatic Index 93.44

Aromaticity 0.0753

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4181.56

LogP -38.26

H-bond Donors 152.0

H-bond Acceptors 140.0

Rotatable Bonds 346.0

Heavy Atoms 714.0

Ring Count 10.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185557 VERIFIED: NO

Provenance & Taxonomy

OrganismBombus terrestris [Animal]

FamilyDefensin

Tax ID30195

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal