Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC344H529N89O104S9

DescriptionStandard

        MLVFSGGNCSLSHKPASALPQDKYCTAILHPEAACLLSECRLYCFNYYNGVGKCKDTKPGGSCVCTYTPSVSY
    

Molecular Weight7864.00 Da

Isoelectric Point (pI)8.12

Net Charge (pH 7.0)1.59

Net Charge (pH 7.4) 1.14

Charge Density (pH 7.0) 0.0218

GRAVY Index-0.02

Hydrophobic Moment 0.38

Boman Index0.10

Instability Index53.28

Aliphatic Index 65.48

Aromaticity 0.1096

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3049.63

LogP -34.05

H-bond Donors 113.0

H-bond Acceptors 117.0

Rotatable Bonds 246.0

Heavy Atoms 546.0

Ring Count 15.0

Amide Bonds 76.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0196396 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence