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MYP_052101
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Basic Information
Cathelicidin (135-146)-CAP7 (1-12), Tylotoin-sC18*
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C128H234N52O29S2
Standard
Sequence
KCVRQNNKRVCKGLRKRLRKFRNK
Physicochemical Analysis
3029.69 Da
12.00
11.73
11.49
0.4889
-1.71
0.79
-0.87
79.02
56.67
0.0417
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1432.50
-16.07
55.0
43.0
114.0
211.0
1.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0064545 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human keratinocytes HaCat
Hemolysis
PMID30389988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
RECORD: Rec_0103096 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus DSM 20030
13.47 μM
MIC
PMID30389988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
RECORD: Rec_0179157 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium TA100
12.64 μM
MIC
PMID30389988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
RECORD: Rec_0199358 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human cervical carcinoma HeLa
100 μM
PMID30389988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
RECORD: Rec_0219110 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30389988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
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