MYP_052038
Basic Information
Ponericin-W5 (ants, insects, animals)
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Insecticidal/Pest control Insecticidal activity
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
Standard
24 amino acids
C127H207N31O27
Standard
Sequence
FWGALIKGAAKLIPSVVGLFKKKQ
Physicochemical Analysis
2600.19 Da
10.60
4.76
4.54
0.1981
0.51
0.60
0.26
-5.55
117.92
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
933.04
-3.34
32.0
32.0
88.0
185.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108793 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal Hemolytic
horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 μl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)
RECORD: Rec_0114639 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Insecticidal
Escherichia coli CIP 548, Escherichia coli L2, Enterobacter cloacae CIP 6085, Klebsiella pneumoniae CIP 8291, S. marcescens LMA TP, F. meningosepticum CIP 6057, Pseudomonas aeruginosa CIP A22,and fungi Saccharomyces cerevisiae LMA 720. Updated 7/2021
RECORD: Rec_0124155 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal
Escherichia coli(Inhibition zone = 3mm)
RECORD: Rec_0132601 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal
Enterococcus faecalis CIP 636(Inhibition zone = 3mm)
RECORD: Rec_0144499 VERIFIED: NO
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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