Peptide Database

Peptide NamePonericin-W5 (ants, insects, animals)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Insecticidal/Pest control ▸ Insecticidal activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC127H207N31O27

DescriptionStandard

        FWGALIKGAAKLIPSVVGLFKKKQ
    

Molecular Weight2600.19 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.1981

GRAVY Index0.51

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index-5.55

Aliphatic Index 117.92

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 933.04

LogP -3.34

H-bond Donors 32.0

H-bond Acceptors 32.0

Rotatable Bonds 88.0

Heavy Atoms 185.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007866 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal

TargetProteus mirabilis LMA TP

Activitynot detected

MethodInhibition zone assay

RECORD: Rec_0007897 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

FamilyPonericin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus megaterium ATCC 9885

Methodantimicrobial inhibition zone assay

RECORD: Rec_0010943 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

FamilyPonericin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis ATCC 6623

Methodantimicrobial inhibition zone assay

RECORD: Rec_0013625 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal

TargetMicrococcus luteus CIP 5345

Activity11 mm

MethodInhibition zone assay

RECORD: Rec_0015697 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

FamilyPonericin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus CIP 677

Methodantimicrobial inhibition zone assay

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