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MYP_051971
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Basic Information
4285(derived from DNA-polymerase domain of HIV-1 RT (20-mers))
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition
Standard
20 amino acids
C104H168N28O30S
Standard
Sequence
SPAIFQSSMTKILEPFRKQN
Physicochemical Analysis
2322.68 Da
9.99
1.46
1.25
0.0730
-0.53
0.65
-0.08
107.72
63.50
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
960.07
-9.83
32.0
33.0
77.0
163.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0266818 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0290123 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Integrase inhibition
35 μM
IC50
PaperPeptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase. PMID15790559 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15790559/
RECORD: Rec_0374354 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of disintegration catalyzed by integrase
100 μM
IC50
PaperPeptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase PMID15790559 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15790559/
RECORD: Rec_0407811 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:Inhibition of 3′-processing catalyzed by integrase
35 μM
IC50
PaperPeptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase PMID15790559 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15790559/
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