Peptide Database

Peptide NameLactocyclicin Q (Bacteriocin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC284H449N77O71

DescriptionStandard

        LIDHLGAPRWAVDTILGAIAVGNLASWVLALVPGPGWAVKAGLATAAAIVKHQGKAAAAAW
    

Molecular Weight6078.08 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.62

Charge Density (pH 7.0) 0.0317

GRAVY Index0.83

Hydrophobic Moment 0.43

Boman Index0.42

Instability Index8.94

Aliphatic Index 126.72

Aromaticity 0.0656

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2264.90

LogP -15.47

H-bond Donors 78.0

H-bond Acceptors 75.0

Rotatable Bonds 186.0

Heavy Atoms 432.0

Ring Count 13.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417741 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus sp. strain QU 12 [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli NBRC 3301

Activity17.3 μM

MethodMIC

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