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MYP_051969
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Basic Information
Lactocyclicin Q (Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
61 amino acids
C284H449N77O71
Standard
Sequence
LIDHLGAPRWAVDTILGAIAVGNLASWVLALVPGPGWAVKAGLATAAAIVKHQGKAAAAAW
Physicochemical Analysis
6078.08 Da
9.70
1.93
1.62
0.0317
0.83
0.43
0.42
8.94
126.72
0.0656
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2264.90
-15.47
78.0
75.0
186.0
432.0
13.0
62.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0257859 VERIFIED: YES
Provenance & Taxonomy
Lactococcus sp. strain QU 12 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli JM109
34.3 μM
MIC
PMID19139222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19139222/
RECORD: Rec_0259972 VERIFIED: YES
Provenance & Taxonomy
Lactococcus sp. strain QU 12 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus subsp. aureus ATCC 12600T
91.6 μM
MIC
PMID19139222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19139222/
RECORD: Rec_0262345 VERIFIED: YES
Provenance & Taxonomy
Lactococcus sp. strain [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
The whole peptide has a cyclic structure in which N and C termini are bound to each other
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
lactis QU 1
0.141 μM
MIC
PaperIdentification and characterization of leucocyclicin Q, a novel cyclic bacteriocin produced by Leuconostoc mesenteroides TK41401. Appl Environ Microbiol. 2011 Nov;77(22):8164-8170. doi: 10.1128/AEM.06348-11. PMID: 21948835. PMID19139222;21948835 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19139222/
RECORD: Rec_0281665 VERIFIED: YES
Provenance & Taxonomy
Lactococcus sp. strain [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
The whole peptide has a cyclic structure in which N and C termini are bound to each other
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis JCM 5803
0.26 μM
MIC
PaperIdentification and characterization of leucocyclicin Q, a novel cyclic bacteriocin produced by Leuconostoc mesenteroides TK41401. Appl Environ Microbiol. 2011 Nov;77(22):8164-8170. doi: 10.1128/AEM.06348-11. PMID: 21948835. PMID19139222;21948835 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19139222/
RECORD: Rec_0281955 VERIFIED: YES
Provenance & Taxonomy
Lactococcus sp. strain QU 12 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Lactococcus lactis QU 1
0.141 μM
MIC
PMID19139222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19139222/
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