Peptide Database

Peptide NameMaximins 8 H7 [Cleaved into: Maximin-8; Maximin-H7]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC705H1163N197O221S3

DescriptionStandard

        MKFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGLKTAVKGALKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVIKTIGGVIGGLLKNLG
    

Molecular Weight16031.16 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.37

Net Charge (pH 7.4) -1.70

Charge Density (pH 7.0) -0.0095

GRAVY Index-0.39

Hydrophobic Moment 0.71

Boman Index-0.08

Instability Index48.15

Aliphatic Index 96.18

Aromaticity 0.0556

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6837.50

LogP -66.25

H-bond Donors 239.0

H-bond Acceptors 224.0

Rotatable Bonds 566.0

Heavy Atoms 1126.0

Ring Count 11.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108338 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Cytolytic Hemolytic