Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC229H361N57O76S4

DescriptionStandard

        MSKFDDFDLDVEKVSKQDSKITPQWKSESVCTPGCATGLLQTCFLQT
    

Molecular Weight5256.91 Da

Isoelectric Point (pI)4.60

Net Charge (pH 7.0)-2.52

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0537

GRAVY Index-0.39

Hydrophobic Moment 0.55

Boman Index-0.03

Instability Index63.69

Aliphatic Index 62.13

Aromaticity 0.0851

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2165.99

LogP -24.14

H-bond Donors 76.0

H-bond Acceptors 78.0

Rotatable Bonds 176.0

Heavy Atoms 366.0

Ring Count 7.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101318 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus amyloliquefaciens [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence