Peptide Database

Peptide NameInterleukin-18

Function Ontology

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC801H1264N212O252S10

DescriptionStandard

        YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
    

Molecular Weight18216.52 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-5.16

Net Charge (pH 7.4) -5.53

Charge Density (pH 7.0) -0.0328

GRAVY Index-0.55

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index37.26

Aliphatic Index 75.10

Aromaticity 0.0955

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7597.54

LogP -75.28

H-bond Donors 262.0

H-bond Acceptors 258.0

Rotatable Bonds 628.0

Heavy Atoms 1275.0

Ring Count 22.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154658 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-1 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor IL-1 family Chemokine-like Angiogenic