Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1030H1558N232O299S9

DescriptionStandard

        IDDLAKVDYSLNSSPAVFRPFIDLDLKGIVYPAGNHTGPPYVAAPFTVPDQSDSMLYLAFSEYFFQTSSFAYYTARAFDITIAEEVKSGKLICFLLFFFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNVAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight22263.35 Da

Isoelectric Point (pI)4.33

Net Charge (pH 7.0)-10.16

Net Charge (pH 7.4) -10.51

Charge Density (pH 7.0) -0.0508

GRAVY Index0.38

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index43.41

Aliphatic Index 94.60

Aromaticity 0.1450

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8384.64

LogP -97.59

H-bond Donors 287.0

H-bond Acceptors 299.0

Rotatable Bonds 708.0

Heavy Atoms 1570.0

Ring Count 42.0

Amide Bonds 213.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304174 VERIFIED: NO

Provenance & Taxonomy

OrganismGrus americana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria