Peptide Database

Peptide NameBrevinin 1Ph

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC184H302N54O62S3

DescriptionStandard

        NAEEERRDGPDGKEETGIPLLPGLAANLCRPIYCTITKNC
    

Molecular Weight4358.89 Da

Isoelectric Point (pI)4.77

Net Charge (pH 7.0)-2.26

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0564

GRAVY Index-0.65

Hydrophobic Moment 0.57

Boman Index-0.12

Instability Index56.61

Aliphatic Index 75.75

Aromaticity 0.0250

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1872.09

LogP -20.93

H-bond Donors 65.0

H-bond Acceptors 63.0

Rotatable Bonds 142.0

Heavy Atoms 303.0

Ring Count 5.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005679 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

FamilyBrevinin

Tax ID8404

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal