Peptide Database

Peptide NameMCA4-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC59H97N17O11S2

DescriptionStandard

        CRFKFRIVIC
    

Molecular Weight1284.64 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.2739

GRAVY Index1.09

Hydrophobic Moment 0.33

Boman Index0.02

Instability Index-14.52

Aliphatic Index 107.00

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 475.04

LogP -1.49

H-bond Donors 20.0

H-bond Acceptors 16.0

Rotatable Bonds 42.0

Heavy Atoms 89.0

Ring Count 2.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008473 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDisulfide bond

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetSalmonella enterica ATCC 13076

Activity30 μM

MethodMIC

RECORD: Rec_0052324 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDisulfide bond

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 25922

Activity40 μM

MethodMIC

RECORD: Rec_0207122 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDisulfide bond

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity15 μM

MethodMIC

RECORD: Rec_0294725 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDisulfide bond

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetListeria monocytogenes ATCC 19115

Activity10 μM

MethodMIC

RECORD: Rec_0317828 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDisulfide bond

Bio-Activity Profile

Function

Hemolytic

TargetChicken RBC [<6% hemolysis at 100 μM]

Activity100 μM

MethodHemolysis