Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length223 amino acids

Chemical FormulaC1137H1724N254O342S9

DescriptionStandard

        PMPIDDFAEVDYSLNSLPAVFQEFIDLDLKGIIYPPGNYTGSPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPMVSLEQDSFTVEIQGSMEVFAVLPDSTTQLLFTMNIAANTSIALNIFDQKLVGSLCLNRLQFSLARSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight24711.93 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.03

Net Charge (pH 7.4) -17.17

Charge Density (pH 7.0) -0.0764

GRAVY Index0.33

Hydrophobic Moment 0.57

Boman Index0.26

Instability Index47.75

Aliphatic Index 97.98

Aromaticity 0.1345

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421178 VERIFIED: NO

Provenance & Taxonomy

OrganismIbidorhyncha struthersii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria