Peptide Database

Peptide Name[Ala11,22,28]VIP

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC139H230N42O40S

DescriptionStandard

        HSDAVFTDNYARLRKQMAVKKALNSILA
    

Molecular Weight3161.64 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.1016

GRAVY Index-0.25

Hydrophobic Moment 0.50

Boman Index-0.10

Instability Index43.68

Aliphatic Index 94.29

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1364.35

LogP -13.76

H-bond Donors 48.0

H-bond Acceptors 45.0

Rotatable Bonds 108.0

Heavy Atoms 222.0

Ring Count 3.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385500 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetPAC1 receptor (Human); VPAC1 receptor (Human); VPAC2 receptor (Human)

Activity1582 nM

MethodEC50